Isaac married Elizabeth Willoughby on 8 Sep 1662 in Westmoreland, Westmoreland, Virginia, British Colonial America. Elizabeth was born on 27 Sep 1635 in Elizabeth City, Virginia, British Colonial America; died in Apr 1672 in Westmoreland, Virginia, British Colonial America; was buried in Apr 1672 in Westmoreland, Virginia, British Colonial America. [Group Sheet] [Family Chart]

Isaac married Elizabeth Allerton() about 1652 in New Haven, New Haven Colony, British Colonial America. Elizabeth was born about 1630 in England; died about 1659 in New Haven, New Haven, Connecticut, United States; was buried in Apr 1660 in New Haven, New Haven, Connecticut, USA. [Group Sheet] [Family Chart]