1792 - 1866 (73 years)
| Anthony Drexel Duke, Sr. | |
| B: | 28 Jul 1918 |
| Manhattan, New York City, New York, United States | |
| D: | 30 Apr 2014 |
| Gainesville, Alachua, Florida, United States | |
| Alice Noel Rutgers | |
| B: | 26 Sep 1919 |
| New Brunswick, Middlesex, New Jersey, United States | |
| M: | 1939 |
| D: | 12 Aug 1980 |
| New London, Connecticut, United States | |
| Elizabeth “Betty” Ordway | |
| B: | 25 Jul 1925 |
| M: | 1947 |
| D: | 18 Apr 1984 |
| Barclay Robertson Duke | |
| B: | 26 Apr 1961 |
| Manhattan, New York City, New York, USA | |
| D: | 17 Dec 1989 |
| East Hampton, Suffolk, New York, USA | |
| Nancy Ann Abendschoen | |
| B: | Abt 1961 |
| M: | 21 Jun 1986 |
| Morris Township, Morris, New Jersey, USA | |
| D: | Yes, date unknown |
| Diane Marie Douglas | |
| B: | 30 May 1933 |
| New York, United States | |
| M: | 1957 |
| D: | 6 May 2015 |
| Southhampton NY | |
| Angier Biddle Duke | |
| B: | 13 Nov 1915 |
| New York City, New York, United States | |
| D: | 29 Apr 1995 |
| Southampton, Suffolk, New York, United States | |
| Angier Buchanan Duke | |
| B: | 8 Dec 1884 |
| Durham, Durham, North Carolina, United States | |
| D: | 3 Sep 1923 |
| Greenwich, Fairfield, Connecticut, United States | |
| Cordelia Drexel Biddle, II | |
| B: | 16 Apr 1898 |
| Philadelphia, Pennsylvania, United States | |
| M: | 28 Apr 1915 |
| Philadelphia, Pennsylvania, United States | |
| D: | 25 Nov 1984 |
| Manhattan, New York City, New York, United States | |
| Mary Lillian Duke | |
| B: | 16 Nov 1887 |
| Durham, Durham, North Carolina, United States | |
| D: | 14 Jun 1960 |
| Durham, Durham, North Carolina, United States | |
| MG Anthony Joseph Drexel Biddle, Jr. | |
| B: | 17 Dec 1897 |
| Philadelphia, Pennsylvania, United States | |
| M: | 16 Jun 1915 |
| United States | |
| D: | 13 Nov 1961 |
| Washington, District of Columbia, United States | |
| Nannie Duke | |
| B: | 21 May 1902 |
| Warren, North Carolina, United States | |
| D: | 3 Oct 1983 |
| Edgecombe, North Carolina, United States | |
| Mabel Clair Duke | |
| B: | 20 Aug 1899 |
| Nash, North Carolina, United States | |
| D: | 9 Jul 1989 |
| Wake, North Carolina, United States | |
| George Washington Duke | |
| B: | 12 Dec 1874 |
| Nash, North Carolina, United States | |
| D: | 7 Apr 1937 |
| Griffin, North Carolina, United States | |
| Mavine Eva Cheaves | |
| B: | 20 Oct 1877 |
| Franklin, North Carolina, United States | |
| M: | 23 Nov 1898 |
| New Hanover, North Carolina, United States | |
| D: | 2 Sep 1915 |
| Griffins Township, Nash, North Carolina, United States | |
| Benjamin Newton Duke | |
| B: | 27 Apr 1855 |
| Durham Township, Orange, North Carolina, United States | |
| D: | 8 Jan 1929 |
| New York City, New York, United States | |
| Sarah Pearson Angier | |
| B: | 19 Feb 1856 |
| Durham Township, Orange, North Carolina, United States | |
| M: | 21 Feb 1877 |
| Durham Township, Orange, North Carolina, United States | |
| D: | 2 Sep 1936 |
| Blowing Rock, Watauga, North Carolina, United States | |
| James Buchanan Duke | |
| B: | 23 Dec 1856 |
| Durham, Durham, North Carolina, United States | |
| D: | 10 Oct 1925 |
| New York City, New York, United States | |
| Lillian Naomi Fletcher | |
| B: | 23 May 1863 |
| Manhattan, New York City, New York, United States | |
| M: | 29 Nov 1904 |
| Camden, New Jersey, United States | |
| D: | 24 Oct 1925 |
| Manhattan, New York County, New York, United States | |
| Arden Duke Cromwell | |
| B: | 11 Jul 1940 |
| Honolulu, Oahu, Honolulu, Hawaii, United States | |
| D: | 12 Jul 1940 |
| Honolulu, Oahu, Honolulu, Hawaii, United States | |
| Doris Duke | |
| B: | 22 Nov 1912 |
| New York City, New York County, New York, United States | |
| D: | 28 Oct 1993 |
| Beverly Hills, Los Angeles, California, United States | |
| James Henry Roberts Cromwell | |
| B: | 4 Jun 1896 |
| New York City, New York County, New York, United States | |
| M: | 13 Feb 1935 |
| Manhattan, New York City, New York, United States | |
| D: | 19 Mar 1990 |
| Mill Valley, Marin, California, United States | |
| Porfirio Enrique Rubirosa Ariza | |
| B: | 22 Jan 1909 |
| El Seibo, Dominican Republic | |
| M: | 1 Sep 1947 |
| Paris, Île-de-France, France | |
| D: | 5 Jul 1965 |
| Paris, Île-de-France, France | |
| Nanaline Lee Holt | |
| B: | 19 Sep 1869 |
| Macon, Bibb, Georgia, United States | |
| M: | 23 Jul 1907 |
| D: | 12 Apr 1962 |
| New York City, New York County, New York, United States | |
| Mary Elizabeth Duke | |
| B: | 17 Nov 1853 |
| Durham, Durham, North Carolina, United States | |
| D: | 6 Apr 1893 |
| New York, United States | |
| Robert E Lyon | |
| B: | 1847 |
| Granville, North Carolina, United States | |
| M: | 26 Feb 1873 |
| Orange, North Carolina, United States | |
| Artelia Roney | |
| B: | 28 Jun 1829 |
| Orange, Almanance, North Carolina, United States | |
| D: | 20 Aug 1858 |
| Haw River, Alamance, North Carolina, United States | |
| Washington Duke | |
| B: | 18 Dec 1820 |
| Orange, North Carolina, United States | |
| M: | 9 Dec 1852 |
| Orange, North Carolina, United States | |
| D: | 8 May 1905 |
| Durham, Orange County, North Carolina, United States | |
| John Roney | |
| B: | 16 Mar 1792 |
| Alamance, North Carolina, United States | |
| D: | 16 Feb 1866 |
| Alamance, North Carolina, United States | |
| Mary Elizabeth Trollinger | |
| B: | 25 Mar 1800 |
| Alamance, North Carolina, United States | |
| D: | 11 Aug 1879 |
| North Carolina, United States | |
