Bef 1604 - 1657 (> 53 years)
| Sally Otis | |
| B: | 4 Oct 1825 |
| New York City, New York, United States | |
| D: | 24 Aug 1894 |
| Bellport, Suffolk, New York, United States | |
| George Theodore Lyman | |
| B: | 23 Dec 1821 |
| Paris, Île-de-France, France | |
| M: | 17 Apr 1845 |
| New York, United States | |
| D: | 14 Jun 1908 |
| Milton, , Massachusetts | |
| William Church Otis | |
| B: | 2 Jul 1831 |
| Cambridge, Middlesex, Massachusetts, United States | |
| D: | 13 Mar 1889 |
| Boston, Suffolk, Massachusetts, United States | |
| James Otis | |
| B: | 12 Oct 1836 |
| New York City, New York, United States | |
| D: | 22 Jul 1898 |
| Bellport, Suffolk, New York, United States | |
| Mary Adelia Ludlum | |
| B: | 1836 |
| New York, United States | |
| M: | 31 Mar 1863 |
| Manhattan, New York City, New York, United States | |
| D: | 4 Jan 1890 |
| Manhattan, New York City, New York, United States | |
| Francis Alleyne Otis | |
| B: | 1842 |
| of New York, United States | |
| D: | 14 Dec 1903 |
| Manhattan, New York, New York, United States | |
| Almira Marie Smith | |
| B: | 1844 |
| New York, United States | |
| M: | 30 Nov 1865 |
| D: | Yes, date unknown |
| Sophia R. Otis | |
| B: | Jul 1829 |
| Providence, Providence, Rhode Island, United States | |
| D: | Abt 1830 |
| Martha Church Otis | |
| B: | 1832 |
| Massachusetts, United States of America | |
| D: | 1 Apr 1833 |
| New York, United States of America | |
| James Otis | |
| B: | Sep 1827 |
| Providence, Providence, Rhode Island, United States | |
| Martha Church Otis | |
| B: | 20 Oct 1823 |
| New York, United States | |
| D: | Nov 1849 |
| James William Otis | |
| B: | 18 May 1800 |
| Massachusetts, United States | |
| D: | 3 Sep 1869 |
| New York, United States | |
| Martha Crapon Church | |
| B: | 1808 |
| Providence, Providence, Rhode Island, United States | |
| M: | 17 Dec 1824 |
| Taunton, Bristol, Massachusetts, United States | |
| D: | 7 May 1888 |
| Manhattan, New York City, New York, United States | |
| US Senator Harrison Gray Otis | |
| B: | 8 Oct 1765 |
| Boston, Suffolk County, Massachusetts, USA | |
| D: | 28 Oct 1848 |
| Boston, Suffolk County, Massachusetts, USA | |
| Sally Foster | |
| B: | 10 Jan 1770 |
| Boston, Suffolk County, Massachusetts, USA | |
| M: | 31 May 1790 |
| Boston, Suffolk County, Massachusetts, USA | |
| D: | 6 Sep 1838 |
| Boston, Suffolk County, Massachusetts, USA | |
| Samuel Allyne Otis | |
| B: | 24 Nov 1740 |
| Barnstable, Barnstable, Massachusetts, United States | |
| D: | 22 Apr 1814 |
| Washington, District of Columbia, United States | |
| Elizabeth Gray | |
| B: | 22 Jun 1744 |
| Boston, Suffolk, Massachusetts, United States | |
| M: | 31 Dec 1764 |
| Barnstable, Barnstable, Massachusetts Bay Colony, British Colonial America | |
| D: | 22 Jan 1779 |
| Boston, Suffolk, Massachusetts, United States | |
| James Otis | |
| B: | 14 Jun 1702 |
| Barnstable, Barnstable, Massachusetts Bay Colony, British Colonial America | |
| D: | 9 Nov 1778 |
| Barnstable, Barnstable, Massachusetts Bay, British Colonial America | |
| Mary Allyn | |
| B: | 10 Nov 1702 |
| Barnstable, Barnstable, Massachusetts, United States | |
| M: | 14 May 1724 |
| Barnstable, Massachusetts Bay, British Colonial America | |
| D: | 21 Apr 1774 |
| Barnstable, Barnstable, Massachusetts, United States | |
| John Otis | |
| B: | 21 Sep 1657 |
| Hingham, Massachusetts Bay Colony, British Colonial America | |
| D: | 23 Sep 1727 |
| Barnstable, Barnstable, Massachusetts Bay Colony, British Colonial America | |
| Mercy Bacon | |
| B: | 28 Feb 1659 |
| Barnstable, Massachusetts Bay, British Colonial America | |
| M: | 18 Jul 1683 |
| Barnstable, Plymouth Colony, British Colonial America | |
| D: | 10 Dec 1737 |
| Barnstable, Massachusetts Bay, British Colonial America | |
| Mary Jacob | |
| B: | Bef 11 May 1632 |
| Hingham, Norfolk, England | |
| D: | Aft 12 Jul 1699 |
| Weymouth, Suffolk, Massachusetts Bay Colony, British Colonial America | |
| John Otis | |
| B: | 14 Jan 1622/3 |
| Barnstable, Devon, England | |
| M: | 10 May 1649 |
| Hingham, Suffolk, Massachusetts Bay Colony, British Colonial America | |
| D: | 16 Jan 1684 |
| Scituate, Plymouth, Colony of Massachusetts, British Colonial America | |
| Captain John Holbrook | |
| B: | Apr 1618 |
| Glastonbury, Somerset, England | |
| D: | 23 Nov 1699 |
| Weymouth, Norfolk, Massachusetts Bay Colony, British Colonial America | |
| Nicolas Jacob | |
| B: | Bef 1604 |
| Hingham, Norfolk, England | |
| D: | 5 Jun 1657 |
| Hingham, Suffolk, Massachusetts Bay, British Colonial America | |
| Mary Gilman | |
| B: | Abt 1608 |
| Hingham, Norfolk, England | |
| D: | 15 Jun 1681 |
| Hingham, Suffolk, Massachusetts Bay Colony, British Colonial America | |
